I was quite excited to see the Rat Monarch being the class for today's daily. I'd say I did fairly well for my second run with the new class. So far, the Bloody Sigil has been fantastic at early levels, Binlor was really great if only to get a guaranteed ENDISWAL for repeated physical resistances buffs, and now I absolutely need to get my hands on a Witchalok Pendant and prep it, regardless of the item size restriction. I quite like the way healing on item purchases makes gold into a tricky resource to manage, not entirely unlike the levels/ratlings were meant to be for the previous incarnation (at least that's the impression I got).
In some way it feels like this class is opposite to the Monk in its approach to levelling up, in that you want to start hitting the boss as early as possible level-wise. Jormungändr went down at level 6, and while that's far from unheard of on other characters, it's significantly earlier than my usual playstyle.
I still need to go and play the Chemist some more, I haven't tried it since the changes.